Takayasu arteritis was diagnosed according to the prede. Women are affected in 80 to 90 percent of cases, with an age of onset that is usually between 10 and 40 years. The first case corresponds to a young woman who met the american college of rheuma tology criteria for takayasu arteritis. Endovascular aortic biopsy in the diagnosis of takayasu arteritis. Takayasus arteri tis is a rare, idiopathic, chronic inflammatory disease with cellmediated inflammation, involving mainly the aorta and its major branches. Takayasu arteritis is an idiopathic granulomatous vasculitis of the aorta and its main branches and it constitutes one of the more common vasculitides in children. Phase i is the systemic or prepulseless period, which is characterized by constitutional symptoms such as lowgrade fever, malaise, night sweats, arthralgia, anorexia, and weight loss. Takayasus arteritis american college of rheumatology. Clinical differentiation between giant cell temporal arteritis and takayasu s arteritis.
Takayasu arteritis genetic and rare diseases information. Takayasu arteritis with coronary and pulmonary involvement in a young child presenting with acute coronary syndrome. Takayasu arteritis tak is a rare inflammatory largevessel vasculitis primarily affecting the aorta and its major branches, but also other large. In asia, takayasu s arteritis is a major cause of high blood pressure in teenagers and young adults. The value of using 18ffdg pet coregistered with enhanced ct in determining vascular lesion sites and in. Clinical features and diagnosis of takayasu arteritis. The american college of rheumatology 1990 criteria for the. Takayasu arteritis ta, also known as idiopathic medial aortopathy or pulseless disease, is a granulomatous large vessel vasculitis that predominantly affects the aorta and its major branches. Takayasu arteritis is a condition that causes inflammation of the main blood vessel that carries blood from the heart to the rest of the body and its associated branched blood vessels. One particularly notable type is cranial arteritis temporal arteritis, a disease of variable duration and unknown cause that is accompanied by fever and involves the temporal and occasionally other arteries of the skull. Citations may include links to fulltext content from pubmed central and publisher web sites. Definicion historia patogenesis epidemiologia cuadro clinico diagnostico tratamiento pronostico 3. The disease results from an attack by the bodys own immune system, causing inflammation in the walls of arteries.
Clinical features and diagnoses of takayasu arteritis. Researching old documents in relation to takayasu arteritis, two papers have been found. At diagnosis, takayasu s arteritis patients often are between the ages of 15 and 35. The exact cause is not well known but the pathology is thought to be similar to giant cell arteritis. Aug 11, 2011 takayasu arteritis is an autoimmune vasculitis that affects the large and medium vessels. As a result of the inflammation, the blood vessel walls become thick and make it difficult for blood to flow. Phase i is the systemic or prepulseless period, which is characterized by constitutional symptoms such as lowgrade fever, malaise. Takayasu arteritis ta is a rare disease affecting chiefly young women, although it can affect both men and women and persons of many different ethnicities. Arteritis is an inflammation in localized segments of arteries.
The presence of any 3 or more criteria yields a sensitivity of 90. Ta primarily affects the aorta and its primary branches table 1. Takayasu arteritis ta is a chronic vasculitis of unknown etiology. Pubmed comprises more than 26 million citations for biomedical literature from medline, life science journals, and online books. Takayasus arteritis in the hospital escuela, tegucigalpa. Takayasu arteritis tak is classified as a largevessel vasculitis because it primarily affects the aorta and its primary branches. Vasculitis is uncommon, and large or median vessel vasculitis, such as takayasu and temporal arteritis, are even more.
Pentraxin3 as a marker of disease activity in takayasu arteritis. Nov 03, 20 takayasu arteritis is a condition that causes inflammation of the main blood vessel that carries blood from the heart to the rest of the body and its associated branched blood vessels. The disease progression is said to occur in a triphasic pattern. Ta carries a high morbidity rate, but importantly, overall mortality has declined over time such that the 15year survival rate has increased from 82. Takayasu s arteritis also known as aortic arch syndrome, nonspecific aortoarteritis, and pulseless disease. Takayasu arteritis if at least 3 of these 6 criteria are present. Lachaud m, houyel l, baruteau a, petit j, gournay v, paul jf. Over time, impaired blood flow causes damage to the heart and various other organs of the body. Takayasus arteritis, also called tak, is a rare form of vasculitis disease involving inflammation in the walls of the largest arteries in the body. Grayson pc, maksimowiczmckinnon k, clark tm, et al. Eleven patients with takayasu arteritis in the active stage, 3 patients with takayasu arteritis in the inactive stage. Abstract we describe the case of a 28yearold woman who presented to our clinic with a history of chronic bilateral visual loss and recent episodes of syncope. Patients with takayasu arteritis can have symptoms like weak or absent pulses in extremities, widely varying blood pressures, and dizziness.
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